全基因组选择模型研究进展及展望

doi:10.11843/j.issn.0366-6964.2019.02.001

Abstract

Abstract:

Genomic selection(GS) is a new approach for selection breeding using high-density single nucleotide polymorphisms (SNPs) across the whole genome, which can shorten the generation interval by early selection, accelerate genetic progress by improving the accuracy of breeding value estimation. GS has a good predictive effect, especially for the complex traits with low heritability and difficult to be measured, and which truly realizes the genomic technology guiding breeding program. With the development of chip and sequencing technology, the detection cost of high-density SNP chips is continuously reduced, the genome-wide selection model is continuously upgraded and optimized, and the prediction accuracy is continuously improved, the whole genome selection has become an important means and research hotspot in animal genetic improvement. At present, genomic selection has made significant progress and becomes a standard method for genetic evaluation in dairy cattle, and its application in other species is being carried out. In this paper, we reviewed the statistical models of genomic selection, summarized its applications in animal breeding, discussed the existing problems, and prospected its development direction and application prospects.

CLC Number:

S114
S813.1

YIN Lilin, MA Yunlong, XIANG Tao, ZHU Mengjin, YU Mei, LI Xinyun, LIU Xiaolei, ZHAO Shuhong. The Progress and Prospect of Genomic Selection Models[J]. ACTA VETERINARIA ET ZOOTECHNICA SINICA, 2019, 50(2): 233-242.

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The Progress and Prospect of Genomic Selection Models

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